University of Virginia



GDT: Generalized Disequilibrium Test

GDT is a software package for family-based genome-wide association analysis. The method GDT (AJHG 85:364-376) examines the allele frequency differences in all phenotypically discordant relative pairs in general pedigrees (including large extended pedigrees with missing founders), and generalizes several "within-family association" tests such as TDT and PDT.

Online Manual

Software Manual in HTML format

Download Program

The latest version of GDT


University of Virginia | Health System